Thursday Night NFL Best Bets

October 16, 2025

🏈 Matchup & Key Context

  • The Steelers are favored by 5.5 points, and the Over/Under is about 44.5.

  • The Bengals are hurting defensively: Trey Hendrickson, a key edge rusher, is expected to be out.

  • Cincinnati also placed TE Mike Gesicki on IR, weakening their tight end group.

  • The Steelers have momentum, winning three straight and performing well on the road.

  • Several pick models favor Pittsburgh – the SportsLine model projects around 46 total points and leans the spread to the Steelers.

🎯 Best Bets & Prop Ideas

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